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Acute Stroke

MedGen UID:
148427
•Concept ID:
C0751956
•
Disease or Syndrome
Synonyms: Acute Cerebrovascular Accident; Acute Cerebrovascular Accidents; Acute Strokes; Cerebrovascular Accident, Acute; Cerebrovascular Accidents, Acute; Stroke, Acute; Strokes, Acute

Definition

The sudden or severe onset of neurological deficit(s) attributable to an acute focal vascular injury of the central nervous system. [from NCI]

Professional guidelines

PubMed

Management of acute ischemic stroke.
Rigual R, Fuentes B, Díez-Tejedor E
Med Clin (Barc) 2023 Dec 7;161(11):485-492. Epub 2023 Jul 31 doi: 10.1016/j.medcli.2023.06.022. PMID: 37532617
Post-stroke Movement Disorders: Clinical Spectrum, Pathogenesis, and Management.
Tater P, Pandey S
Neurol India 2021 Mar-Apr;69(2):272-283. doi: 10.4103/0028-3886.314574. PMID: 33904435
Diagnosis and management of acute ischaemic stroke.
Hurford R, Sekhar A, Hughes TAT, Muir KW
Pract Neurol 2020 Aug;20(4):304-316. Epub 2020 Jun 7 doi: 10.1136/practneurol-2020-002557. PMID: 32507747Free PMC Article

Recent clinical studies

Etiology

Risk prediction models for deep venous thrombosis in patients with acute stroke: A systematic review and meta-analysis.
Fu H, Hou D, Xu R, You Q, Li H, Yang Q, Wang H, Gao J, Bai D
Int J Nurs Stud 2024 Jan;149:104623. Epub 2023 Oct 19 doi: 10.1016/j.ijnurstu.2023.104623. PMID: 37944356
Visual symptoms in acute stroke - A systematic review of observational studies.
Helboe KS, Eddelien HS, Kruuse C
Clin Neurol Neurosurg 2023 Jun;229:107749. Epub 2023 May 4 doi: 10.1016/j.clineuro.2023.107749. PMID: 37163931
Neuroimaging of Acute Stroke.
Jadhav AP, Desai SM, Liebeskind DS, Wechsler LR
Neurol Clin 2020 Feb;38(1):185-199. Epub 2019 Nov 7 doi: 10.1016/j.ncl.2019.09.004. PMID: 31761058
Causes of Acute Stroke: A Patterned Approach.
Knight-Greenfield A, Nario JJQ, Gupta A
Radiol Clin North Am 2019 Nov;57(6):1093-1108. doi: 10.1016/j.rcl.2019.07.007. PMID: 31582037Free PMC Article
Stroke chameleons.
Dupre CM, Libman R, Dupre SI, Katz JM, Rybinnik I, Kwiatkowski T
J Stroke Cerebrovasc Dis 2014 Feb;23(2):374-8. Epub 2013 Aug 15 doi: 10.1016/j.jstrokecerebrovasdis.2013.07.015. PMID: 23954604

Diagnosis

Visual symptoms in acute stroke - A systematic review of observational studies.
Helboe KS, Eddelien HS, Kruuse C
Clin Neurol Neurosurg 2023 Jun;229:107749. Epub 2023 May 4 doi: 10.1016/j.clineuro.2023.107749. PMID: 37163931
Role of the nurse in acute stroke care.
Clare CS
Nurs Stand 2020 Apr 1;35(4):68-75. Epub 2020 Mar 30 doi: 10.7748/ns.2020.e11482. PMID: 32227723
Causes of Acute Stroke: A Patterned Approach.
Knight-Greenfield A, Nario JJQ, Gupta A
Radiol Clin North Am 2019 Nov;57(6):1093-1108. doi: 10.1016/j.rcl.2019.07.007. PMID: 31582037Free PMC Article
Acute Stroke.
Morotti A, Poli L, Costa P
Semin Neurol 2019 Feb;39(1):61-72. Epub 2019 Feb 11 doi: 10.1055/s-0038-1676992. PMID: 30743293
Vascular imaging: ultrasound.
Rodriguez-Luna D, Molina CA
Handb Clin Neurol 2016;136:1055-64. doi: 10.1016/B978-0-444-53486-6.00055-7. PMID: 27430458

Therapy

Evaluation of acute mechanical revascularization in large stroke (ASPECTS ⩽5) and large vessel occlusion within 7 h of last-seen-well: The LASTE multicenter, randomized, clinical trial protocol.
Costalat V, Lapergue B, Albucher JF, Labreuche J, Henon H, Gory B, Sibon I, Boulouis G, Cognard C, Nouri N, Richard S, Marnat G, Di Maria F, Annan M, Duhamel A, Cagnazzo F, Jovin T, Arquizan C; LASTE Trial Investigators
Int J Stroke 2024 Jan;19(1):114-119. Epub 2023 Jul 31 doi: 10.1177/17474930231191033. PMID: 37462028
Evidence of High-Intensity Exercise on Lower Limb Functional Outcomes and Safety in Acute and Subacute Stroke Population: A Systematic Review.
Mah SM, Goodwill AM, Seow HC, Teo WP
Int J Environ Res Public Health 2022 Dec 22;20(1) doi: 10.3390/ijerph20010153. PMID: 36612471Free PMC Article
Cognitive Impairment and Dementia After Stroke: Design and Rationale for the DISCOVERY Study.
Rost NS, Meschia JF, Gottesman R, Wruck L, Helmer K, Greenberg SM; DISCOVERY Investigators
Stroke 2021 Aug;52(8):e499-e516. Epub 2021 May 27 doi: 10.1161/STROKEAHA.120.031611. PMID: 34039035Free PMC Article
Endovascular Treatment of Acute Ischemic Stroke.
Silva GS, Nogueira RG
Continuum (Minneap Minn) 2020 Apr;26(2):310-331. doi: 10.1212/CON.0000000000000852. PMID: 32224754
Efficacy and safety of minimally invasive surgery with thrombolysis in intracerebral haemorrhage evacuation (MISTIE III): a randomised, controlled, open-label, blinded endpoint phase 3 trial.
Hanley DF, Thompson RE, Rosenblum M, Yenokyan G, Lane K, McBee N, Mayo SW, Bistran-Hall AJ, Gandhi D, Mould WA, Ullman N, Ali H, Carhuapoma JR, Kase CS, Lees KR, Dawson J, Wilson A, Betz JF, Sugar EA, Hao Y, Avadhani R, Caron JL, Harrigan MR, Carlson AP, Bulters D, LeDoux D, Huang J, Cobb C, Gupta G, Kitagawa R, Chicoine MR, Patel H, Dodd R, Camarata PJ, Wolfe S, Stadnik A, Money PL, Mitchell P, Sarabia R, Harnof S, Barzo P, Unterberg A, Teitelbaum JS, Wang W, Anderson CS, Mendelow AD, Gregson B, Janis S, Vespa P, Ziai W, Zuccarello M, Awad IA; MISTIE III Investigators
Lancet 2019 Mar 9;393(10175):1021-1032. Epub 2019 Feb 7 doi: 10.1016/S0140-6736(19)30195-3. PMID: 30739747Free PMC Article

Prognosis

Swallowing Dysfunction after Acute Stroke: The Incidence, Predictors and Outcome.
Londhe C, Agrawal A, Pednekar S, Pandey D, Khan MF
J Assoc Physicians India 2023 Aug;71(8):11-12. doi: 10.59556/japi.71.0301. PMID: 37651239
Women and Ischemic Stroke: Disparities and Outcomes.
Cherian L
Neurol Clin 2023 May;41(2):265-281. Epub 2023 Feb 13 doi: 10.1016/j.ncl.2022.10.001. PMID: 37030957
Stroke mimics: incidence, aetiology, clinical features and treatment.
H Buck B, Akhtar N, Alrohimi A, Khan K, Shuaib A
Ann Med 2021 Dec;53(1):420-436. doi: 10.1080/07853890.2021.1890205. PMID: 33678099Free PMC Article
Delirium post-stroke.
McManus J, Pathansali R, Stewart R, Macdonald A, Jackson S
Age Ageing 2007 Nov;36(6):613-8. Epub 2007 Oct 25 doi: 10.1093/ageing/afm140. PMID: 17965033
CAST: randomised placebo-controlled trial of early aspirin use in 20,000 patients with acute ischaemic stroke. CAST (Chinese Acute Stroke Trial) Collaborative Group.
Lancet 1997 Jun 7;349(9066):1641-9. PMID: 9186381

Clinical prediction guides

ERASER.
Fiehler J, Thomalla G, Bernhardt M, Kniep H, Berlis A, Dorn F, Eckert B, Kemmling A, Langner S, Remonda L, Reith W, Rohde S, Möhlenbruch M, Bendszus M, Forkert ND, Gellissen S
Stroke 2019 May;50(5):1275-1278. doi: 10.1161/STROKEAHA.119.024858. PMID: 31009356
Machine Learning-Based Model for Prediction of Outcomes in Acute Stroke.
Heo J, Yoon JG, Park H, Kim YD, Nam HS, Heo JH
Stroke 2019 May;50(5):1263-1265. doi: 10.1161/STROKEAHA.118.024293. PMID: 30890116
Stroke chameleons.
Dupre CM, Libman R, Dupre SI, Katz JM, Rybinnik I, Kwiatkowski T
J Stroke Cerebrovasc Dis 2014 Feb;23(2):374-8. Epub 2013 Aug 15 doi: 10.1016/j.jstrokecerebrovasdis.2013.07.015. PMID: 23954604
Dysphagia bedside screening for acute-stroke patients: the Gugging Swallowing Screen.
Trapl M, Enderle P, Nowotny M, Teuschl Y, Matz K, Dachenhausen A, Brainin M
Stroke 2007 Nov;38(11):2948-52. Epub 2007 Sep 20 doi: 10.1161/STROKEAHA.107.483933. PMID: 17885261
Clinical interpretation and use of stroke scales.
Kasner SE
Lancet Neurol 2006 Jul;5(7):603-12. doi: 10.1016/S1474-4422(06)70495-1. PMID: 16781990

Recent systematic reviews

Risk prediction models for deep venous thrombosis in patients with acute stroke: A systematic review and meta-analysis.
Fu H, Hou D, Xu R, You Q, Li H, Yang Q, Wang H, Gao J, Bai D
Int J Nurs Stud 2024 Jan;149:104623. Epub 2023 Oct 19 doi: 10.1016/j.ijnurstu.2023.104623. PMID: 37944356
A systematic review and synthesis of global stroke guidelines on behalf of the World Stroke Organization.
Mead GE, Sposato LA, Sampaio Silva G, Yperzeele L, Wu S, Kutlubaev M, Cheyne J, Wahab K, Urrutia VC, Sharma VK, Sylaja PN, Hill K, Steiner T, Liebeskind DS, Rabinstein AA
Int J Stroke 2023 Jun;18(5):499-531. Epub 2023 Mar 1 doi: 10.1177/17474930231156753. PMID: 36725717Free PMC Article
Early mobilization in acute stroke phase: a systematic review.
Mariana de Aquino Miranda J, Mendes Borges V, Bazan R, José Luvizutto G, Sabrysna Morais Shinosaki J
Top Stroke Rehabil 2023 Mar;30(2):157-168. Epub 2021 Dec 20 doi: 10.1080/10749357.2021.2008595. PMID: 34927568
Society for Vascular Surgery clinical practice guidelines for management of extracranial cerebrovascular disease.
AbuRahma AF, Avgerinos ED, Chang RW, Darling RC 3rd, Duncan AA, Forbes TL, Malas MB, Murad MH, Perler BA, Powell RJ, Rockman CB, Zhou W
J Vasc Surg 2022 Jan;75(1S):4S-22S. Epub 2021 Jun 19 doi: 10.1016/j.jvs.2021.04.073. PMID: 34153348
Acute stroke intervention: a systematic review.
Prabhakaran S, Ruff I, Bernstein RA
JAMA 2015 Apr 14;313(14):1451-62. doi: 10.1001/jama.2015.3058. PMID: 25871671

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